50/50

First things first. I've never been a big Seth Rogen fan. However, after watching the trailer I may have been converted...
I've not been able to find the UK trailer so here's the US one instead

A young man turns a devastating illness into a unique opportunity to experience life in 50/50, a funny, touching and original story about friendship, love and survival starring Joseph Gordon-Levitt and Seth Rogen.

Adam Lerner (Joseph Gordon-Levitt) has a pretty great life—with a talented, sexy artist girlfriend and a great job, the 27-year old seems to have it all. But when Adam begins to suffer with agonizing back pain, he discovers that he has a rare and possibly fatal form of cancer. With a massive, malignant tumor growing along his spinal column, his life changes in a heartbeat. Coffee shops give way to chemotherapy clinics, art openings to counseling sessions and plans for the future to strategies for survival.

Writer Will Reiser experienced his own personal battle with cancer, and was inspired to write an original story which reflects the humor and heartbreak which collide in a touching and often hilarious journey through a world in which a young man is completely unprepared for. His best friend, Kyle (Seth Rogen), uses Adam’s condition to lure girls into sympathy sex, his overbearing mother (Anjelica Huston) loses sight of him in her own fears, his otherwise-occupied girlfriend, Rachael (Bryce Dallas Howard) tries to distract herself an increasingly frantic social life, and Katherine (Anna Kendrick), the young therapist assigned to his case, struggles to keep up with the needs of her third client ever in an unexpectedly funny movie that reminds us that sometimes laughter really is the best medicine.

Hitting UK cinemas November 25, 2011